Mike van Bokhoven wrote:
   Cromemco
DPU? Z80 and 68000 on one S-100 card; add an IOP Serial I/O
 card, and you've got another Z80... 
 How about the Sega MegaDrive/Genesis? That ran a 68000 and Z80. 
 
 That's only two, though :) I'm mainly curious as to which vendors
 managed to produce and market a system with more than two out of the
 box (rather than relying on add-on boards from third parties, or even
 optional extras from the manufacturer). I don't think there could
 have been many.  
Amstrad produced a 386 PC with a built-in Megadrive. So that's three.
Four if you count the keyboard :-)
Antonio